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5-Amino-1MQ research compound – vial, Peptiva

Peptiva

Research Compound 5-Amino-1MQ

€68,00
Sale price  €68,00 Regular price  €80,00
Strength50 mg
Format

FOR IN VITRO LABORATORY RESEARCH ONLY.
Not intended for personal, clinical, diagnostic or veterinary use, or for administration to humans or animals.

MAIN RESEARCH AREAS Research profile

NNMT inhibicija in vitro Primary
Adipocitna biologija Very common
Metabolizam energije Common
Modeli debljine (životinjski) Secondary

Editorial map of the main themes found in the scientific literature. Bar length is not a statistical score, efficacy rating, or indication for human use.

Description and specifications

Research Compound 5-Amino-1MQ is a laboratory material for analytical and in vitro work, with a total declared content of 50 mg.

What is 5-Amino-1MQ?

5-Amino-1MQ (5-amino-1-methylquinolinium) is a small organic molecule, not a peptide. It is a quaternary quinolinium cation with a molecular weight of approximately 159 Da, studied as a selective inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT).

Research background

The compound was developed at the University of Texas Medical Branch as part of screening quinolinium analogues as NNMT inhibitors. Results in cellular and mouse metabolic models were published in 2018.

Mechanism and scientific context

NNMT transfers a methyl group from S-adenosylmethionine to nicotinamide, producing 1-methylnicotinamide. It thereby links vitamin B3 metabolism (and, indirectly, NAD+) to cellular methylation metabolism. NNMT inhibition is studied as a way of influencing nicotinamide availability and cellular energetics in adipocytes.

Main research areas

  • NNMT inhibition
  • nicotinamide metabolism and NAD+ pathways
  • methylation metabolism
  • adipocyte cell models

Level of evidence

Predominantly preclinical. Quality human data are not available.

Related

A related area is covered by NAD+.


Research use only: for laboratory, analytical and in vitro research only; not for use in humans or animals. Guidance on batch documentation is available in our COA guide.

Peptides Without Myths — Scientific Handbook (PDF)

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Explore the scientific context in greater depth

The expanded guide covers more than 50 compounds, mechanisms of action, levels of evidence, limitations of the available data and research regimens reported in publicly available scientific literature.

  • 50+ compounds covered in detail
  • Preclinical and clinical data clearly distinguished
  • Experimental approaches described in scientific literature
  • COA, purity and documentation

Educational content is not medical advice, a recommendation for self-administration or instructions for using products sold in this store.

COA on request

To enquire about a certificate of analysis (COA), send the material name, requested variant and LOT / batch number if available. Documents are not published on this page.

Request a COA by email

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A COA applies to a specific batch and documents the analytical parameters tested for that batch. The product is intended strictly for laboratory, analytical and in vitro research.

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Anonymous

Definitivno ponovno naručujem.

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Anonymous

Komunikacija 10/10.

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Anonymous

Paket stigao uredno.

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Anonymous

Uzeo zajedno s MOTS-c. Sve super.

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Anonymous

5-Amino-1MQ sam dugo tražio. Drago mi je da ga imate.