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Peptiva
Research Compound HGH Fragment 176-191
€59,50
Sale price
€59,50
Regular price
€70,00
FOR IN VITRO LABORATORY RESEARCH ONLY.
Not intended for personal, clinical, diagnostic or veterinary use, or for administration to humans or animals.
MAIN RESEARCH AREAS Research profile
Editorial map of the main themes found in the scientific literature. Bar length is not a statistical score, efficacy rating, or indication for human use.
Description and specifications
Research Compound HGH Fragment 176-191 is a laboratory material for analytical and in vitro work.
What is HGH Fragment 176-191?
HGH Fragment 176-191 is a synthetic 16-amino-acid peptide corresponding to the C-terminal region of human growth hormone (residues 176–191), with a molecular weight of approximately 1.8 kDa. Unlike full-length growth hormone, which has 191 amino acids and two disulfide bridges, the fragment contains only a small part of the sequence.
Research background
Research into C-terminal fragments of growth hormone was carried out in the 1990s at Monash University in Australia, with the aim of separating the metabolic effects of GH from its growth-promoting effects. The same line of research produced the modified analogue AOD-9604.
Mechanism and scientific context
In adipocyte and animal models the fragment is associated with regulation of lipolysis and lipogenesis. According to published work it does not bind significantly to the GH receptor and does not show a pronounced effect on IGF-1 levels in models, which distinguishes it from full-length somatropin. The precise receptor mechanism has not been elucidated.
Main research areas
- growth hormone fragments
- adipocyte biology
- lipolysis and lipogenesis in models
- structure–function relationships of GH
Level of evidence
Predominantly preclinical. Quality clinical data are not available.
Related
See the GH/IGF signalling collection.
Research use only: for laboratory, analytical and in vitro research only; not for use in humans or animals. Guidance on batch documentation is available in our COA guide.
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COA on request
To enquire about a certificate of analysis (COA), send the material name, requested variant and LOT / batch number if available. Documents are not published on this page.
Request a COA by emailThe button opens your email app with a prepared enquiry. You send the message yourself. peptivapeptides@protonmail.com
A COA applies to a specific batch and documents the analytical parameters tested for that batch. The product is intended strictly for laboratory, analytical and in vitro research.