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Peptiva
Research Compound Kisspeptin
€55,25
Sale price
€55,25
Regular price
€65,00
FOR IN VITRO LABORATORY RESEARCH ONLY.
Not intended for personal, clinical, diagnostic or veterinary use, or for administration to humans or animals.
MAIN RESEARCH AREAS Research profile
Editorial map of the main themes found in the scientific literature. Bar length is not a statistical score, efficacy rating, or indication for human use.
Description and specifications
Research Compound Kisspeptin is a laboratory material for analytical and in vitro work. The exact declared peptide form is stated in the batch specification.
What is kisspeptin?
Kisspeptins are a family of peptides produced by cleavage of the protein encoded by the KISS1 gene. The main forms are kisspeptin-54 (also known as metastin), kisspeptin-14, -13 and -10. All share the same C-terminal decapeptide, which is sufficient for receptor activation.
Research background
The KISS1 gene was discovered in 1996 in Hershey, Pennsylvania, as a suppressor of melanoma metastasis, which gave it its name. Only in 2003 did research into the genetics of puberty show that mutations in its receptor disrupt the reproductive axis, moving kisspeptin to the centre of reproductive neuroendocrinology.
Mechanism and scientific context
Kisspeptin activates the KISS1R receptor (formerly GPR54), a G-protein-coupled receptor expressed on hypothalamic GnRH neurons. Activation stimulates GnRH release and, consequently, LH and FSH release from the pituitary. Kisspeptin is therefore considered a key upstream control point of the reproductive axis.
Main research areas
- KISS1R signalling
- GnRH neurons
- the LH/FSH axis
- metastasis biology (the original context of discovery)
Level of evidence
Preclinical and experimental human data exist from research studies. Kisspeptin is not an approved medicine, and these data do not confirm the properties of this material.
Related
See the Reproductive endocrinology collection and the materials HCG and HMG.
Research use only: for laboratory, analytical and in vitro research only; not for use in humans or animals. Guidance on batch documentation is available in our COA guide.
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- Experimental approaches described in scientific literature
- COA, purity and documentation
Educational content is not medical advice, a recommendation for self-administration or instructions for using products sold in this store.
COA on request
To enquire about a certificate of analysis (COA), send the material name, requested variant and LOT / batch number if available. Documents are not published on this page.
Request a COA by emailThe button opens your email app with a prepared enquiry. You send the message yourself. peptivapeptides@protonmail.com
A COA applies to a specific batch and documents the analytical parameters tested for that batch. The product is intended strictly for laboratory, analytical and in vitro research.