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Peptiva peptides
Research Compound Human Menopausal Gonadotropin (HMG)
€42,50
Sale price
€42,50
Regular price
€50,00
FOR IN VITRO LABORATORY RESEARCH ONLY.
Not intended for personal, clinical, diagnostic or veterinary use, or for administration to humans or animals.
Laboratory dispenser format
This description applies to the dispenser-format variant, not the vial-format variant.
The dispenser is a laboratory packaging and material-dispensing format. Product identity, declared quantity and storage conditions are stated in the specification for the individual material.
Laboratory dispensing format. It is not an injection or medical device and is not intended for administration to humans or animals.
MAIN RESEARCH AREAS Research profile
Editorial map of the main themes found in the scientific literature. Bar length is not a statistical score, efficacy rating, or indication for human use.
Description and specifications
Research Material HMG (human menopausal gonadotropin) is a laboratory material for analytical and in vitro work, available in a 75 IU variant.
What is hMG?
Human menopausal gonadotropin (menotropin) is not a single molecule but a preparation containing the biological activity of two glycoprotein hormones: follicle-stimulating hormone (FSH) and luteinising hormone (LH). Activity is expressed in international units for each hormone separately.
Research background
The preparation was developed in the 1950s and 1960s, when the Italian chemist Piero Donini devised a process for extracting gonadotropins from the urine of postmenopausal women, in whom their concentration is elevated. Pharmaceutical hMG preparations have their own regulatory documentation.
Mechanism and scientific context
FSH and LH act via separate G-protein-coupled receptors (FSHR and LHCGR) on different gonadal cells. Both hormones share the alpha subunit, with specificity conferred by the beta subunit. The ratio of FSH to LH activity in the preparation is key to its profile.
Main research areas
- FSH and LH receptor biology
- glycoprotein hormones
- folliculogenesis in experimental models
- standardisation of biological activity
Analytical considerations
Because it is a mixture of hormones, characterisation is more complex than for a single short peptide: the activity of each component must be determined separately.
Related
See also HCG.
Research use only: for laboratory, analytical and in vitro research only; not for use in humans or animals. Not a medicine. Guidance on batch documentation is available in our COA guide.
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Educational content is not medical advice, a recommendation for self-administration or instructions for using products sold in this store.
COA on request
To enquire about a certificate of analysis (COA), send the material name, requested variant and LOT / batch number if available. Documents are not published on this page.
Request a COA by emailThe button opens your email app with a prepared enquiry. You send the message yourself. peptivapeptides@protonmail.com
A COA applies to a specific batch and documents the analytical parameters tested for that batch. The product is intended strictly for laboratory, analytical and in vitro research.