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Peptiva peptides
Research Compound Somatropin (HGH)
€76,50
Sale price
€76,50
Regular price
€90,00
FOR IN VITRO LABORATORY RESEARCH ONLY.
Not intended for personal, clinical, diagnostic or veterinary use, or for administration to humans or animals.
Laboratory dispenser format
This description applies to the dispenser-format variant, not the vial-format variant.
The dispenser is a laboratory packaging and material-dispensing format. Product identity, declared quantity and storage conditions are stated in the specification for the individual material.
Laboratory dispensing format. It is not an injection or medical device and is not intended for administration to humans or animals.
MAIN RESEARCH AREAS Research profile
Editorial map of the main themes found in the scientific literature. Bar length is not a statistical score, efficacy rating, or indication for human use.
Description and specifications
Research Compound Somatropin is a laboratory material for analytical and in vitro work, available in a 36 IU variant.
What is somatropin?
Somatropin is recombinant human growth hormone: a 191-amino-acid protein with two disulfide bridges and a molecular weight of approximately 22 kDa. Its sequence is identical to the main form of growth hormone secreted by the pituitary.
Research background
Growth hormone was formerly obtained from the pituitaries of deceased donors. Recombinant somatropin was developed in the early 1980s and, after 1985, completely replaced pituitary-derived hormone once it was found that the pituitary preparation could transmit Creutzfeldt-Jakob disease. It was one of the first recombinant proteins in widespread use.
Mechanism and scientific context
A single GH molecule binds two GH receptors simultaneously, activating the kinase JAK2 and the transcription factor STAT5. Downstream, GH stimulates IGF-1 synthesis in the liver and other tissues. Biological activity depends on correct protein folding, not just chemical purity.
Main research areas
- the GH receptor and JAK2/STAT5 signalling
- the GH/IGF axis
- recombinant protein production
- protein folding and stability
Analytical considerations
As a large protein, somatropin is susceptible to aggregation and deamidation. HPLC purity is not sufficient to confirm biological activity, which requires additional analyses.
Related
See also IGF-1 LR3 and the GH/IGF signalling collection.
Research use only: for laboratory, analytical and in vitro research only; not for use in humans or animals. Not a medicine. Guidance on batch documentation is available in our COA guide.
PEPTIVA PRO E-BOOK · DIGITAL EDITION
Explore the scientific context in greater depth
The expanded guide covers more than 50 compounds, mechanisms of action, levels of evidence, limitations of the available data and research regimens reported in publicly available scientific literature.
- 50+ compounds covered in detail
- Preclinical and clinical data clearly distinguished
- Experimental approaches described in scientific literature
- COA, purity and documentation
Educational content is not medical advice, a recommendation for self-administration or instructions for using products sold in this store.
COA on request
To enquire about a certificate of analysis (COA), send the material name, requested variant and LOT / batch number if available. Documents are not published on this page.
Request a COA by emailThe button opens your email app with a prepared enquiry. You send the message yourself. peptivapeptides@protonmail.com
A COA applies to a specific batch and documents the analytical parameters tested for that batch. The product is intended strictly for laboratory, analytical and in vitro research.