Research Compound L-Carnitine

€45,00

€45,00 €80,00

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MAIN RESEARCH AREAS Research profile

Fatty acid transport (mitochondrial) Primary

Energy metabolism Very common

In vitro lipid oxidation Common

Cellular bioenergetics Secondary

Editorial map of the main themes found in the scientific literature. Bar length is not a statistical score, efficacy rating, or indication for human use.

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Specifications and available formats

Strength	1200 mg
Format	Vial · Research dispenser

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Description and research information

Research Compound L-Carnitine is a laboratory material for analytical and in vitro work, with a total declared content of 1200 mg.

What is L-carnitine?

L-carnitine (β-hydroxy-γ-trimethylaminobutyrate) is a naturally occurring quaternary ammonium compound, not a peptide, with a molecular weight of approximately 161 Da. It is synthesised in the body from the amino acids lysine and methionine, mainly in the liver and kidneys.

Research background

Carnitine was isolated from muscle extracts in 1905, which gave it its name (Latin carnis, flesh). Its key role in transporting fatty acids into mitochondria was clarified only in the 1950s, making it one of the foundations of our understanding of cellular energy metabolism.

Mechanism and scientific context

Long-chain fatty acids cannot cross the inner mitochondrial membrane on their own. The carnitine shuttle solves this in three steps: the enzyme CPT1 attaches the fatty acid to carnitine, the translocase CACT carries acylcarnitine across the membrane, and CPT2 converts it back to acyl-CoA for beta-oxidation.

Main research areas

the carnitine shuttle (CPT1, CACT, CPT2)
mitochondrial beta-oxidation
acylcarnitine profiles
cellular energy homeostasis

Level of evidence

The biochemical role is very well established. The effects of additional carnitine depend on the model and research question and cannot be generalised.

Research use only: for laboratory, analytical and in vitro research only; not for use in humans or animals. Guidance on batch documentation is available in our COA guide.

Storage and handling

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