PEPTIVA PEPTIDES
Research Compound Semax
Peptiva
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Full shipping terms →MAIN RESEARCH AREAS Research profile
Editorial map of the main themes found in the scientific literature. Bar length is not a statistical score, efficacy rating, or indication for human use.
| Strength | 10 mg |
|---|---|
| Format | Lyophilised vial · Research dispenser |
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Research Compound Semax is a laboratory material for analytical and in vitro work.
Semax is a synthetic heptapeptide with the sequence Met-Glu-His-Phe-Pro-Gly-Pro and a molecular weight of approximately 813 Da. It consists of the ACTH(4-7) fragment with an added stabilising Pro-Gly-Pro sequence.
Semax was developed at the Institute of Molecular Genetics of the Russian Academy of Sciences in the 1980s. It built on research showing that short ACTH fragments have neurobiological activity independent of the hormonal action of full-length ACTH on the adrenal gland.
In animal models Semax is associated with increased expression of the neurotrophin BDNF and its receptor TrkB in the hippocampus, modulation of dopaminergic and serotonergic systems, and changes in gene expression in models of cerebral ischaemia. Semax lacks the corticotropic activity of full-length ACTH.
Predominantly preclinical, with limited human literature from regional studies.
Related materials include Selank and DSIP.
Research use only: for laboratory, analytical and in vitro research only; not for use in humans or animals. Guidance on batch documentation is available in our COA guide.
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PEPTIVA PRO E-BOOK · DIGITAL EDITION
The expanded guide covers more than 50 compounds, mechanisms of action, levels of evidence, limitations of the available data and research regimens reported in publicly available scientific literature.
Educational content is not medical advice, a recommendation for self-administration or instructions for using products sold in this store.
For in vitro laboratory research only. Not intended for personal, clinical, diagnostic or veterinary use, or for administration to humans or animals.
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