Peptiva

Research Compound GHRP-2

€51,00

€51,00 €60,00

Strength 10 mg 5 mg

Format Lyophilised vial Research dispenser

FOR IN VITRO LABORATORY RESEARCH ONLY.
Not intended for personal, clinical, diagnostic or veterinary use, or for administration to humans or animals.

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MAIN RESEARCH AREAS Research profile

GH secretagogue signalling Primary

Ghrelin receptors Very common

Endocrine pharmacology Common

Somatotropic axis Secondary

Editorial map of the main themes found in the scientific literature. Bar length is not a statistical score, efficacy rating, or indication for human use.

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Specifications and available formats

Strength	10 mg · 5 mg
Format	Lyophilised vial · Research dispenser

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Description and research information

Research Compound GHRP-2 is a laboratory material for analytical and in vitro work.

What is GHRP-2?

GHRP-2 (also known as pralmorelin) is a synthetic hexapeptide with the sequence D-Ala-D-2Nal-Ala-Trp-D-Phe-Lys-NH2 and a molecular weight of approximately 818 Da. It contains several D-amino acids and the non-natural amino acid naphthylalanine, which increase resistance to enzymatic degradation.

Research background

GHRP-2 was developed as a successor to the earlier GHRP-6 in research on synthetic growth hormone secretagogues. In Japan it has been used as a diagnostic pharmacological tool for assessing pituitary function.

Mechanism and scientific context

GHRP-2 is an agonist of the GHS-R1a receptor, the same receptor targeted by endogenous ghrelin. Activation on pituitary somatotrophs stimulates GH release independently of the GHRH receptor. Pharmacological studies also describe effects on ACTH, cortisol and prolactin, distinguishing it from more selective compounds such as ipamorelin.