PEPTIVA PEPTIDES
Research Compound IGF-1 LR3
Peptiva
FOR IN VITRO LABORATORY RESEARCH ONLY.
Not intended for personal, clinical, diagnostic or veterinary use, or for administration to humans or animals.
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Editorial map of the main themes found in the scientific literature. Bar length is not a statistical score, efficacy rating, or indication for human use.
| Strength | 1 mg |
|---|---|
| Format | Lyophilised vial · Research dispenser |
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Research Compound IGF-1 LR3 is a laboratory material for analytical and in vitro work.
IGF-1 LR3 (Long R3 IGF-1) is a recombinant analogue of insulin-like growth factor 1. It consists of 83 amino acids: the full 70-amino-acid IGF-1 sequence in which glutamic acid at position 3 is replaced by arginine (hence “R3”), plus a 13-amino-acid N-terminal extension (hence “Long”). The molecular weight is approximately 9.1 kDa.
The analogue was developed in Australia in the 1990s. Because of its stability and high activity in cell culture, it is widely used as a supplement in cell culture media in research and bioprocessing laboratories, giving it a clear in vitro context.
The modifications substantially reduce binding to IGF-binding proteins (IGFBPs), which otherwise limit IGF-1 availability. As a result it is more active than native IGF-1 at the same concentration in cellular systems. It activates the IGF-1 receptor and the downstream PI3K/AKT/mTOR and Ras/MAPK pathways.
Predominantly experimental and bioprocessing literature. Clinical data for native IGF-1 are not evidence for IGF-1 LR3.
Research use only: for laboratory, analytical and in vitro research only; not for use in humans or animals. Guidance on batch documentation is available in our COA guide.
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PEPTIVA PRO E-BOOK · DIGITAL EDITION
The expanded guide covers more than 50 compounds, mechanisms of action, levels of evidence, limitations of the available data and research regimens reported in publicly available scientific literature.
Educational content is not medical advice, a recommendation for self-administration or instructions for using products sold in this store.
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