PEPTIVA PEPTIDES
Research Compound Thymosin Alpha-1
Peptiva
FOR IN VITRO LABORATORY RESEARCH ONLY.
Not intended for personal, clinical, diagnostic or veterinary use, or for administration to humans or animals.
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Editorial map of the main themes found in the scientific literature. Bar length is not a statistical score, efficacy rating, or indication for human use.
| Strength | 5 mg |
|---|---|
| Format | Lyophilised vial · Research dispenser |
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Research Compound Thymosin Alpha-1 is a laboratory material for analytical and in vitro work.
Thymosin Alpha-1 (Tα1) is an N-acetylated peptide of 28 amino acids with a molecular weight of approximately 3108 Da. It is derived from the larger precursor protein prothymosin alpha.
Tα1 was isolated in 1977 by Allan Goldstein's research group from a fraction of thymic extracts known as thymosin fraction 5. A synthetic form (thymalfasin) was later developed as a regulated pharmaceutical preparation in some countries, so a clinical literature also exists for specific indications.
The literature describes effects on dendritic cells and T-lymphocyte maturation, and interactions with Toll-like receptors (notably TLR2 and TLR9) and MyD88-dependent signalling. These pathways link innate and adaptive immunity, making Tα1 a common model in immune regulation research.
Preclinical and clinical data exist for specific pharmaceutical preparations. They cannot be attributed to this research material, whose identity and quality are confirmed only by batch documentation.
Despite the similar name, Thymosin Alpha-1 is not related to thymosin beta-4 (TB-500). For other immune-related peptides see KPV, LL-37 and Thymalin.
Research use only: for laboratory, analytical and in vitro research only; not for use in humans or animals. Guidance on batch documentation is available in our COA guide.
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The expanded guide covers more than 50 compounds, mechanisms of action, levels of evidence, limitations of the available data and research regimens reported in publicly available scientific literature.
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